FRONTIER
  • FRONTIER
  • INGREDIENTS
  • FORMULATIONS
  • EVENT
  • TOPIC
FRONTIER
  • FRONTIER
  • INGREDIENTS
  • FORMULATIONS
  • EVENT
  • TOPIC
Login Registered
Provide Info
Add Topics
Chelerythrine

What is chelerythrine

Chelerythrine is the benzo phenanthridine alkaloid present in the plant Chelidonium majus (larger Chelidonium).It is an effective, selective and cell permeable protein kinase C inhibitor in vitro and G protein-coupled CB1 receptor antagonist.


It is also found in the plants Zanthoxylum clava-herculis and Zanthoxylum rhoifolium, exhibiting antibacterial activity against Staphylococcus aureus and other human pathogens.


图片14.png



图片15.png


Key benefits


Type 2 diabetes mellitus

Type 2 diabetes (T2DM) is a common metabolic syndrome that is characterized by insulin resistance, hyperglycemia and dyslipidemia.Some data fundamentally elucidate the mechanism by which chelerythrine retains the benefits of improving insulin sensitivity while reducing the adverse effects of TZDs, suggesting that the natural product chelerythrine is a very promising pharmacological agent by selectively targeting PPARγ for further development in the clinical treatment of insulin resistance.

 

Antimanic effect

Chelerythrine is a well-known protein kinase C inhibitor .And it may have antimanic effects and additional dose and time response studies are warranted to further evaluate its range of activity.







COMMENTS
COMMENTS
Welcome to win-health!
Top Ingredients
More

Early studies have shown that this compound possesses a plethora...  More

2017-10-16
  • 1
  • 1

​Ginger is a plant with leafy stems and yellowish green flowers....  More

2017-10-23
  • 0
  • 0

Echinacoside products in Xinjiang mainly, Inner Mongolia Alxa Le...  More

2017-10-16
  • 0
  • 0

Introduce the function of HMB-Ca,it can reduce the loss of lean ...  More

2017-10-16
  • 0
  • 1

Arecoline is an alkaloid natural product found in the areca nut,...  More

2017-09-21
  • 0
  • 0

Turmeric is a spice from turmeric plants. It is commonly used in...  More

2017-09-21
  • 1
  • 1

Glycyrrhizic acid(or glycyrrhizin) is the main sweet ingredient ...  More

2017-09-21
  • 0
  • 0

Emodin (from Rheum emodi, a Himalayan rhubarb) is a purgative re...  More

2017-09-21
  • 2
  • 0

Pumpkin seeds are powerful, nutrient-rich superfoods that contai...  More

2017-10-26
  • 0
  • 0

Chelerythrine is the benzo phenanthridine alkaloid present in th...  More

2017-09-21
  • 0
  • 0

Arbutin is a glycoside; a glycosylated hydroquinone extracted fr...  More

2017-10-31
  • 0
  • 0

  More

2018-03-26
  • 0
  • 0