PQQ, also known as Pyrroloquinoline quinone, is an essential micronutrient as a critical role in human health. It has been shown to protect existing mitochondria from oxidative damage and has ability to create new mitochondria throughout the body and the brain, which believed the primary way to prevent of aging. PQQ supports healthy mitochondrial structure and function to help maintain healthy mental functions like recall, memory and cognition as we age.

In fact, PQQ is key in enabling cells to undergo spontaneous mitochondrial biogenesis. Like essential nutrients, the immune system seems particularly sensitive to low levels of PQQ. With PQQ deprivation there are multiple defects in immune function and loss of white blood cells to respond properly.

Benefits of PQQ

•Protects brain cells

•Potential neuro-protectant

•Improved cognitive function and memory

•Antioxidant effects

•Cardiovascular improvement

•Enhanced nerve growth

Promotes Brain Health

PQQ protects the brain against neurotoxicity induced by other powerful toxins, including mercury, glutamate, and oxidopamine, and has unique ability to activate cell signaling pathways directly involved in cellular energy metabolism, development, and function. It promotes the spontaneous generation of new mitochondria within aging cells by increasing levels of PGC 1-alpha (the human chemical that triggers mitochondrial growth).

By protecting neurons by modulating the properties of the N-methyl-D-aspartate (NMDA) receptor, PQQ reducing excitotoxicity—the damaging consequence of long-term overstimulation of neurons that is associated with many neurodegenerative diseases and seizures.

In recently Parkinson’s disease research, PQQ showed potential abilities that preventing development of alpha-synuclein and protecting against the self-oxidation of the DJ-1 gene, which means PQQ can help in the treatment of these disease.

Linked with Alzheimer’s disease, PQQ can protects nerve cells from the damaging effects of the beta-amyloid-protein and prompts CREB, a protein that regulates DNA function and gene expression. This indicates that PQQ also plays an important role in this treatment area.

In a word, PQQ is superior to metoprolol in protecting mitochondria from ischemia and reperfusion oxidative damage

Supports Heart Function

PQQ is considered a super-antioxidant because it is far more stable than most other antioxidants and can carry out more redox cycling reactions. PQQ also has specific cardiovascular benefits by protecting against oxidative stress through its rejuvenating effects. PQQ can offer benefits to heart attack victims and reduces the size of damaged areas in myocardial infarction models.

In conclusion, PQQ can help you fight the signs of aging, turn the lights on for your mitochondria and keep your vital systems running the way they should. You can get better cellular energy, and find your own “fountain of youth”.

Tips and dates

PQQ has been shown to be at least 100 times more efficient than vitamin C and all phenolic compounds tested to date in redox cycling potential.

PQQ and CoQ10 are both involved in mitochondrial energy production. In the group receiving PQQ along with CoQ10, the results were even more dramatic.

Safety & Dosage

PQQ has been studied in humans in dosages up to 60 mg/day with no observed side effects or toxicities. The current recommendation is 10-20 mg daily. There are some clinical studies that justify the dosage, especially the 20 mg dosage for enhancing memory.